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Summary:Process for obtaining leucauramine derivatives, in particular for obtaining a salt of N- (2-carboxyphenyl) leucauramine or N- (4-carboxyphenyl) leucauramine, characterized in that anthranilic acid is reacted in any order, p-aminobenzcic with a compound of formula: ** (see formula) ** Wherein z represents oxygen or sulfur and w represents hydrogen or alkyl, and a hydroxide, alkoxide, carbonate or bicarbonate of a group iia metal, ammonia, a primary, secondary or tertiary amine, a quaternary ammonium hydroxide, or a hydrazine, hydroxylamine or guanidine which may optionally carry alkyl or aryl substituents. (Machine-translation by Google Translate, not legally binding)
Bibliography:Application Number: US19710177112