HALOGENATION OF STEROIDS

A process for converting 17 alpha -vinyl-17 beta -hydroxy steroids to 17-(2-haloethylidene)-steroids, known intermediates for antifungal and progestational agents, by treating the 17 alpha -vinyl-17 beta -hydroxy steroids with vanadium tetrahalide.

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Bibliographic Details
Main Authors KRUBINER A,US, OLIVETO E,US
Format Patent
LanguageEnglish
Published 13.02.1973
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Summary:A process for converting 17 alpha -vinyl-17 beta -hydroxy steroids to 17-(2-haloethylidene)-steroids, known intermediates for antifungal and progestational agents, by treating the 17 alpha -vinyl-17 beta -hydroxy steroids with vanadium tetrahalide.
Bibliography:Application Number: USD3716530