AMINOMETHYL PYRAZOLONE DERIVATIVES OF NICOTINAMIDE

1,146,183. Derivatives of nicotinamide. STABILIMENTI CHIMICO-FARMACEUTICI DR. R. RAVASINI & CIA. S.p.A. 9 June, 1966 [1 July, 1965; 12 May, 1966], No. 25836/66. Heading C2C. [Also in Division A5] Novel derivatives of nicotinamide of the formula wherein R is C 1-6 alkyl, or an arylalkyl group whi...

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Main Authors FERIANO BANCI, EZIO TUBARO
Format Patent
LanguageEnglish
Published 07.01.1969
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Summary:1,146,183. Derivatives of nicotinamide. STABILIMENTI CHIMICO-FARMACEUTICI DR. R. RAVASINI & CIA. S.p.A. 9 June, 1966 [1 July, 1965; 12 May, 1966], No. 25836/66. Heading C2C. [Also in Division A5] Novel derivatives of nicotinamide of the formula wherein R is C 1-6 alkyl, or an arylalkyl group which may or may not have substituents in the aromatic nucleus; the substituents being, if present, halogen atoms, hydroxy or methoxy groups are prepared by reacting in a suitable solvent at a temperature of 20‹ to 100‹ C. the appropriate 1 - phenyl - 2,3 - dimethyl - 4- alkylamino-S-pyrazolone with nicotinamide and formaldehyde, in a molar ratio ranging from 1:1 1 to 1: 1: 4 respectively.
Bibliography:Application Number: USD3420839