COMPOSITE SEPARATION MEDIA

A layered separation media includes a fibrous layer including a non-woven media; and a first coating disposed on the non-woven media, the first coating comprising a crosslinked hydrogel; and a membrane layer including a membrane; and a second coating disposed on the membrane. The second coating may...

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Bibliographic Details
Main Authors Hauser, Bradly G, Goertz, Matthew P, Sontag, Stephen K
Format Patent
LanguageEnglish
Published 03.10.2024
Subjects
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
THEIR RELEVANT APPARATUS
TRANSPORTING
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Summary:A layered separation media includes a fibrous layer including a non-woven media; and a first coating disposed on the non-woven media, the first coating comprising a crosslinked hydrogel; and a membrane layer including a membrane; and a second coating disposed on the membrane. The second coating may also include a crosslinked hydrogel. The layered separation media may be used in a system for membrane chromatography. A method of separating a protein from a liquid stream may include flowing the liquid stream through the layered separation media. The protein may bind with functional groups in the hydrogel. The layered separation media may have a DBC10 of 50 mg/mL or greater.
Bibliography:Application Number: US202418621873