NOVEL THERAPEUTIC METHOD FOR ENHANCING MITOCHONDRIAL FUNCTION, TREATING MITOCHONDRIAL DISEASES THEREBY, AND COMPOUNDS USED THEREIN

Novel therapeutic uses of compounds for enhancing mitochondrial function and treating a mitochondrial disease are discovered by artificial intelligence (AI)-based in silico approaches. Methods of enhancing mitochondrial function and/or treating mitochondrial disease include administering an active c...

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Bibliographic Details
Main Authors KIM, Jinhan, SO, Minyoung, SONG, Sangok, JIN, Sanghyung
Format Patent
LanguageEnglish
Published 03.10.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Novel therapeutic uses of compounds for enhancing mitochondrial function and treating a mitochondrial disease are discovered by artificial intelligence (AI)-based in silico approaches. Methods of enhancing mitochondrial function and/or treating mitochondrial disease include administering an active compound to a subject in need. The active compound may be one or more compounds selected from the group consisting of preladenant, cinepazide, mitiglinide, deforolimus, mycophenolate-mofetil, megestrol, lercanidipine, fusidic acid, nimodipine, nicardipine, nitrendipine, benidipine, methazolamide, diethylcarbamazine, and pharmaceutically acceptable salts thereof.
Bibliography:Application Number: US202118262721