SMALL MOLECULE MODULATORS OF FERROPTOSIS

Provided herein are inhibitors of GPX4, pharmaceutical compositions comprising the inhibitory compounds, and methods for using the GPX4 inhibitory compounds for the modulation of ferroptosis and treatment of disease.

Saved in:
Bibliographic Details
Main Authors AZOFEIFA, Joseph, HARRIS, Jason R, GOLIAEI, Ardeshir, MARTIN, Eric, READ, Timothy, DICKSON, John K, WINIGRAD, Zoe
Format Patent
LanguageEnglish
Published 26.09.2024
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:Provided herein are inhibitors of GPX4, pharmaceutical compositions comprising the inhibitory compounds, and methods for using the GPX4 inhibitory compounds for the modulation of ferroptosis and treatment of disease.
Bibliography:Application Number: US202418441446