NON-RIBOSOMAL SEQUENCE ENRICHMENT AND SINGLE-STRANDED DNA LIBRARY FOR NUCLEIC ACID GUIDED NUCLEASE TARGETING

The present invention provides methods for selectively depleting unwanted sequences from a pool of nucleic acids, including (1) methods that can be used to deplete an unwanted sequence from a single-stranded DNA library, and (2) methods that can be used to deplete an unwanted non-polyadenylated RNA...

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Bibliographic Details
Main Authors KRISPIN, Manuel Bernhard, GOURGUECHON, Stephane B
Format Patent
LanguageEnglish
Published 19.09.2024
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Summary:The present invention provides methods for selectively depleting unwanted sequences from a pool of nucleic acids, including (1) methods that can be used to deplete an unwanted sequence from a single-stranded DNA library, and (2) methods that can be used to deplete an unwanted non-polyadenylated RNA from a pool of single-stranded RNA molecules. By depleting the unwanted sequences, the methods enrich a sample for sequences of interest.
Bibliography:Application Number: US202218577037