IL-2 MUTEINS FOR TREATING CANCER OR INFECTION

Provided herein are IL-2 muteins that bind to the IL-2 receptor β subunit but do not have measurable binding to the IL-2 receptor a subunit. Also provided are compositions, kits, methods, and uses involving such IL-2 muteins.

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Bibliographic Details
Main Authors Fayad, Ghassan N, Starling, Gary C, Sriraman, Venkataraman, Kim, Peter S, Cheng, Alan C, Ranganath, Sheila H, Juan, Veronica M, Walsh, Nicole C, Alvarez, Juan C, Hall, Brian E
Format Patent
LanguageEnglish
Published 19.09.2024
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Summary:Provided herein are IL-2 muteins that bind to the IL-2 receptor β subunit but do not have measurable binding to the IL-2 receptor a subunit. Also provided are compositions, kits, methods, and uses involving such IL-2 muteins.
Bibliography:Application Number: US202218578343