PROCESSES FOR THE PREPARATION OF (S)-2-(4-CHLORO-2-METHOXYPHENYL)-2-((3 -METHOXY-5-(M ETHYLSULFONYL)PHENYL)AMINO)-1 -(1H-INDOL-3-YL)ETHENONE DERIVATIVES
The present invention relates to novel chiral synthesis of mono- or di-substituted indole compounds of formula (I)wherein:R1 is H, R2 is F and R3 is H or CH3,R1 is H, CH3 or F, R2 is OCH3 and R3 is H andR1 is H, R2 is OCH3 and R3 is CH3,R1 is CH3, R2 is F and R3 is H,R1 is CF3 or OCF3, R2 is H and R...
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| Format | Patent |
| Language | English |
| Published |
19.09.2024
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| Online Access | Get full text |
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| Abstract | The present invention relates to novel chiral synthesis of mono- or di-substituted indole compounds of formula (I)wherein:R1 is H, R2 is F and R3 is H or CH3,R1 is H, CH3 or F, R2 is OCH3 and R3 is H andR1 is H, R2 is OCH3 and R3 is CH3,R1 is CH3, R2 is F and R3 is H,R1 is CF3 or OCF3, R2 is H and R3 is H,R1 is OCF3, R2 is OCH3 and R3 is H andR1 is OCF3, R2 is H and R3 is CH3. |
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| AbstractList | The present invention relates to novel chiral synthesis of mono- or di-substituted indole compounds of formula (I)wherein:R1 is H, R2 is F and R3 is H or CH3,R1 is H, CH3 or F, R2 is OCH3 and R3 is H andR1 is H, R2 is OCH3 and R3 is CH3,R1 is CH3, R2 is F and R3 is H,R1 is CF3 or OCF3, R2 is H and R3 is H,R1 is OCF3, R2 is OCH3 and R3 is H andR1 is OCF3, R2 is H and R3 is CH3. |
| Author | Wu, Kai Coesemans, Erwin Oost, Rik Schweitzer-Chaput, Bertrand Eriksson, Carl Arne Magnus |
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| RelatedCompanies | Janssen Pharmaceuticals, Inc |
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| Snippet | The present invention relates to novel chiral synthesis of mono- or di-substituted indole compounds of formula (I)wherein:R1 is H, R2 is F and R3 is H or... |
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| Title | PROCESSES FOR THE PREPARATION OF (S)-2-(4-CHLORO-2-METHOXYPHENYL)-2-((3 -METHOXY-5-(M ETHYLSULFONYL)PHENYL)AMINO)-1 -(1H-INDOL-3-YL)ETHENONE DERIVATIVES |
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