METHIONINE ADENOSYLTRANSFERASE 2A INHIBITOR

The present invention provides a methionine adenosyltransferase 2A inhibitor. The structure of the methionine adenosyltransferase 2A inhibitor is as represented by general formula (I), and the definitions of substituents are as described in the specification. The present invention further provides a...

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Main Authors TIAN, Zhoushan, WU, Jian, ZHANG, Huan, Zuo, Rui, ZHOU, Qiuhua, DAI, Qingyu, MA, Changyou, ZHU, Chunxia, HUANG, Dandan, MA, Li, XU, Dan, MIAO, Lei, SU, Jincai, Wu, Yebin
Format Patent
LanguageEnglish
Published 29.08.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides a methionine adenosyltransferase 2A inhibitor. The structure of the methionine adenosyltransferase 2A inhibitor is as represented by general formula (I), and the definitions of substituents are as described in the specification. The present invention further provides a preparation method therefor. A compound represented by formula I provided by the present invention has significant methionine adenosyltransferase 2A inhibitory activity, and can be used in the treatment of diseases mediated by overexpression of methionine adenosyltransferase 2A.
Bibliography:Application Number: US202218566584