Stable, concentrated radionuclide complex solutions

The present invention relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradat...

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Bibliographic Details
Main Authors Brambati, Clementina, de Palo, Francesco, Tesoriere, Giovanni, Chicco, Daniela, Fugazza, Lorenza, Barbato, Donato, Mariani, Maurizio
Format Patent
LanguageEnglish
Published 29.08.2024
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Summary:The present invention relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradation. The use of two stabilizers introduced during the manufacturing process at different stages was found to be of particular advantage.
Bibliography:Application Number: US202418640917