Non-Invasive Assessment Of Glymphatic Flow And Neurodegeneration From A Wearable Device

A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodeg...

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Bibliographic Details
Main Authors Dagum, Paul, Kaplan, Jonathan I, Weber, Carl J, Giovangrandi, Laurent B, Whipple, Nathan, Kovacs, Gregory T.A, Student, Joerg C
Format Patent
LanguageEnglish
Published 15.08.2024
Subjects
DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
MEDICAL OR VETERINARY SCIENCE
SURGERY
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Summary:A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodegeneration, or a neuroimaging marker of neurodegeneration. A target prediction model is output based on the function mapping. The target prediction model can receive new neurophysiological and neurovascular data and output a predicted marker of neurodegeneration.
Bibliography:Application Number: US202418636234