ENGINEERED CELLS FOR THERAPY
Strategies, systems, compositions, and methods for genetically modifying cells to include one or more loss-of-function modifications and/or to include one or more gain-of-function modifications, as well as modified cells (and compositions of such cells) that include one or more loss-of-function modi...
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Main Authors | , |
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Format | Patent |
Language | English |
Published |
01.08.2024
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Subjects | |
Online Access | Get full text |
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Summary: | Strategies, systems, compositions, and methods for genetically modifying cells to include one or more loss-of-function modifications and/or to include one or more gain-of-function modifications, as well as modified cells (and compositions of such cells) that include one or more loss-of-function modifications and/or that include one or more gain-of-function modifications, are described. In certain aspects, such modified cells include at least one gain-of-function modification within a coding region of an essential gene. |
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Bibliography: | Application Number: US202218289461 |