IL4I1 INHIBITORS AND METHODS OF USE
The invention discloses a synthesizing method of benzimidazole derivant and intermediate, which is characterized by the following: proceeding arylation among aryl halide and primary amine; adopting L-pro as additive, cuprous iodide as catalyst; proceeding molecular arylation coupling reaction for ar...
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Main Authors | , , , , , , , , , , , , , , , , , , |
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Format | Patent |
Language | English |
Published |
25.07.2024
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Subjects | |
Online Access | Get full text |
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Summary: | The invention discloses a synthesizing method of benzimidazole derivant and intermediate, which is characterized by the following: proceeding arylation among aryl halide and primary amine; adopting L-pro as additive, cuprous iodide as catalyst; proceeding molecular arylation coupling reaction for aryl iodide or aryl bromide and primary amine; adopting iodo phenylamine compound and bromophenylamine compound as starting material; synthesizing the material through several-step transformation. |
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Bibliography: | Application Number: US202218556196 |