SARS-COV-2 MPRO INHIBITOR COMPOUNDS

The invention described herein relates to compounds of Formula (1b):or a salt thereof, wherein R1, R1a, R2, R3 and R5 are defined herein, and their use in the treatment of SARS-CoV-2 and related viruses and disorders associated with SARS-CoV-2.

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Bibliographic Details
Main Authors PICKWORTH, Mark, DE GRAAF, Chris, HIGUERUELO, Alicia Perez, CONGREVE, Miles Stuart, CHRISTOPHER, John Andrew, MASON, Jonathan Stephen
Format Patent
LanguageEnglish
Published 04.07.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention described herein relates to compounds of Formula (1b):or a salt thereof, wherein R1, R1a, R2, R3 and R5 are defined herein, and their use in the treatment of SARS-CoV-2 and related viruses and disorders associated with SARS-CoV-2.
Bibliography:Application Number: US202218553596