RECOMBINANT ANTIGEN PRESENTING CELLS

The present disclosure provides recombinant antigen presenting cells and methods of use thereof in the culture and expansion of immune cells ex vivo. In some aspects, immune cells expanded through co-culture of the recombinant antigen presenting cells disclosed herein are administered to a subject t...

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Main Authors LI, Wanwen, SOBHANA, Nandhu, YEH, Jane, BADKAR, Shruti, GUPTA, Manoj, MISHRA, Rabi, BENEZER, Gil, SHl, Xi, NAKAMURA, Akito, CHANG, Hui-Hsin, LUO, Mengyao, SONI, Mansi, MAI, Doanh, CAO, Lan, NG, Mei Rosa, BOTHUN, Alisha
Format Patent
LanguageEnglish
Published 04.07.2024
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present disclosure provides recombinant antigen presenting cells and methods of use thereof in the culture and expansion of immune cells ex vivo. In some aspects, immune cells expanded through co-culture of the recombinant antigen presenting cells disclosed herein are administered to a subject to treat a disease or condition in the subject, e.g., to treat a cancer.
Bibliography:Application Number: US202218557559