COMPOUND USED AS SHP2 INHIBITOR AND USE THEREOF

The present invention relates to a compound used as an SHP2 inhibitor and the use thereof. Specifically, the compound of the present invention has a structure as represented by formula I′, wherein the definitions of each group and each substituent are as described in the description. The compound ha...

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Bibliographic Details
Main Authors NIU, Chengshan, LIANG, Apeng, WU, Yusheng, CHEN, Shaoqing, LI, Jun, ZHENG, Maolin
Format Patent
LanguageEnglish
Published 13.06.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a compound used as an SHP2 inhibitor and the use thereof. Specifically, the compound of the present invention has a structure as represented by formula I′, wherein the definitions of each group and each substituent are as described in the description. The compound has a high inhibitory effect on the activity of the SHP2 phosphatase, and can be used for preventing or treating SHP2-related diseases.
Bibliography:Application Number: US202218577261