VARIABLE-VOLUME CHEMOSTAT AND APPLICATIONS THEREOF
A chemostat comprises a chamber containing media with cells; an input tube for delivering nutrient-laden media that support cell growth and division within the chamber at an inflow rate; and an output tube for withdrawing a sample from the chamber at an outflow rate. The inflow and outflow rates are...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
06.06.2024
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Subjects | |
Online Access | Get full text |
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Summary: | A chemostat comprises a chamber containing media with cells; an input tube for delivering nutrient-laden media that support cell growth and division within the chamber at an inflow rate; and an output tube for withdrawing a sample from the chamber at an outflow rate. The inflow and outflow rates are regulated such that the chemostat is operable in a sample accumulation phase in which the outflow rate is zero and the inflow rate increases in proportion to an instantaneous volume of media in the chamber so as to accumulate the sample without changes in a metabolic state within the chamber, or a sample withdrawal phase in which the outflow rate is regulated at a higher rate than the inflow rate to withdraw the accumulated sample from the chamber rapidly at one time and the inflow rate remains in proportion to the instantaneous volume to maintain chemostasis in the chamber. |
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Bibliography: | Application Number: US202318527801 |