N-(HYDROXYALKYL (HETERO)ARYL) TETRAHYDROFURAN CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS

Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharm...

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Main Authors Hadida Ruah, Sara S, Durrant, Steven John, Schmidt, Yvonne, Carvalho Meireles, Lidio Marx, Shaw, David Matthew, Knegtel, Ronald Marcellus, Dodd, James, Galan, Bhairavi, Chudyk, Ewa Iwona, Pontillo, Joseph, Stamos, Dean, Etxebarria Jardi, Gorka, Wray, Christopher, Virani, Anisa Nizarali, Hurley, Dennis James, O'Donnell, Michael Edward, Ahmad, Nadia M, Neubert, Timothy Donald, Pinder, Joanne Louise, Thomson, Stephen Andrew, Pullin, Robert, Skerratt, Sarah, Zhou, Jinglan, North, Kiri, Beck, Elizabeth Mary
Format Patent
LanguageEnglish
Published 06.06.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
Bibliography:Application Number: US202318491021