DETECTION OF STAGE I LUNG CANCER BIOMARKERS

VOCs in exhaled breath can be used to diagnose stage 1 lung cancer (SL1C). Three potential biomarkers Acetoin, Dodecane, and p-Cymene have predictive power for SL1C. Acetoin and Dodecane are predictive with relation to their concentrations in the 1 L breath sample, and p-Cymene is predictive 5 with...

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Bibliographic Details
Main Authors Crainiceanu, Ciprian M, Rule, Ana Maria, Yarmus, Lonny B
Format Patent
LanguageEnglish
Published 16.05.2024
Subjects
DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
PHYSICS
SURGERY
TESTING
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Summary:VOCs in exhaled breath can be used to diagnose stage 1 lung cancer (SL1C). Three potential biomarkers Acetoin, Dodecane, and p-Cymene have predictive power for SL1C. Acetoin and Dodecane are predictive with relation to their concentrations in the 1 L breath sample, and p-Cymene is predictive 5 with relation to being above or below the limit of detection. The diagnostic of the present invention is capable of detecting S1LC noninvasively and in some cases earlier than other methodologies. This diagnostic can then be paired with appropriate treatments to address S1LC before it grows or metastasizes.
Bibliography:Application Number: US202218548767