HSD17B13 INHIBITORS AND/OR DEGRADERS

Described herein are compounds of Formula I,wherein the variables are defined herein, their use as HSD17B13 inhibitors and/or degraders, pharmaceutical compositions containing such compounds and their use to treat, for example, NAFLD and NASH.

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Bibliographic Details
Main Authors Dutra, Jason Kenneth, Adams, Jan Antoinette Cusi Romero, O'Neil, Steven Victor, Bechle, Bruce Michael, Zhang, Lei, Nason, II, Deane Milford, Rankic, Danica Antonia, Zhang, Liying, Edmonds, David James, Garnsey, Michelle Renee, Lee, Jisun, Wright, Ann Sorrentino, Hou, Xinjun, Wang, Yang
Format Patent
LanguageEnglish
Published 09.05.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Described herein are compounds of Formula I,wherein the variables are defined herein, their use as HSD17B13 inhibitors and/or degraders, pharmaceutical compositions containing such compounds and their use to treat, for example, NAFLD and NASH.
Bibliography:Application Number: US202318482129