PYRROLOPYRIMIDINE ITK INHIBITORS

Disclosed herein are arylpyridinone compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structures of Formulas (I)-(IV):wherein the R groups, m, n, and X are as defined in the detailed description. Methods of inhibition of ITK activity in a h...

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Bibliographic Details
Main Authors JACOBSEN, Eric Jon, ANDERSON, David Randolph, HEIER, Richard, HOCKERMAN, Susan Landis, MUKHERJEE, Paramita, BLINN, James Robert
Format Patent
LanguageEnglish
Published 25.04.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Disclosed herein are arylpyridinone compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structures of Formulas (I)-(IV):wherein the R groups, m, n, and X are as defined in the detailed description. Methods of inhibition of ITK activity in a human or animal subject are also provided.
Bibliography:Application Number: US202318383301