PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING

The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I:wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.

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Bibliographic Details
Main Authors SUTHERLIN, Daniel, STANLEY, Mark S, SAVAGE, Scott J, CASTANEDO, Georgette M, MALESKY, Kimberly, WANG, Shumei, GUNZNER-TOSTE, Janet L, DINA, Michael S, KOEHLER, Michael F.T, BAO, Liang, LALONDE, Rebecca L, REYNOLDS, Mark E
Format Patent
LanguageEnglish
Published 11.04.2024
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I:wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.
Bibliography:Application Number: US202318381304