SINGLE-DOMAIN ANTIBODY AGAINST CD16A AND USE THEREOF

The present invention relates to an isolated anti-CD16A single-domain antibody, and a monospecific antibody molecule or a multispecific antibody molecule comprising the anti-CD16A single-domain antibody as a moiety. The present invention also relates to a nucleic acid encoding the anti-CD16A single-...

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Bibliographic Details
Main Authors ZHOU, Shuaixiang, HU, Siyi
Format Patent
LanguageEnglish
Published 28.03.2024
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Summary:The present invention relates to an isolated anti-CD16A single-domain antibody, and a monospecific antibody molecule or a multispecific antibody molecule comprising the anti-CD16A single-domain antibody as a moiety. The present invention also relates to a nucleic acid encoding the anti-CD16A single-domain antibody, the monospecific antibody molecule, or the multispecific antibody molecules, a host cell comprising the nucleic acid, and a method for preparing the anti-CD16A single-domain antibody, the monospecific antibody molecule, or the multispecific antibody molecule. Furthermore, the present invention relates to use of the anti-CD16A single-domain antibody, the monospecific antibody molecule, or the multispecific antibody molecule for the treatment and/or prevention or diagnosis of acute and chronic infectious diseases (e.g., bacterial or viral infections) or a tumor.
Bibliography:Application Number: US202218262937