METHOD OF PRODUCING A MESODERMAL-LINEAGE PRIMITIVE STREAK CELL

A method of producing a mesodermal-lineage primitive streak cell includes a first step of culturing pluripotent stem cells in a medium containing FGF2, BMP (bone morphogenetic protein) 4, a GSK-3β inhibitor, and retinoic acid or a derivative thereof and a second step of culturing cells obtained in t...

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Bibliographic Details
Main Authors KASAHARA, Tomoko, SUETA, Shinichi, OSAFUNE, Kenji
Format Patent
LanguageEnglish
Published 08.02.2024
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Summary:A method of producing a mesodermal-lineage primitive streak cell includes a first step of culturing pluripotent stem cells in a medium containing FGF2, BMP (bone morphogenetic protein) 4, a GSK-3β inhibitor, and retinoic acid or a derivative thereof and a second step of culturing cells obtained in the first step in a medium containing FGF2, a GSK-3β inhibitor, and BMP7.
Bibliography:Application Number: US202318487457