PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES

The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need...

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Main Authors DAGOSTIN, Claudio, BRAIN, Christopher Thomas, CONGREVE, Miles Stuart, BROOKS, Clinton A, SUNG, Moo Je, LI, Yue, BESONG, Gilbert, LU, Yipin, SMITH, Troy, WRONA, Wojciech, HOWARD, Steven, HE, Guo, HOU, Ying, MORTENSON, Paul, WOODHEAD, Steven, LAGU, Bharat
Format Patent
LanguageEnglish
Published 08.02.2024
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Summary:The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.
Bibliography:Application Number: US202218069646