TARGETING MICRORNA TO REGULATE NATIVE GENE FUNCTION BY GENOME EDITING

The disclosure provides plants, plant parts, plant cells, seeds and grain containing a targeted genetic modification that inserts an endogenous microRNA recognition sequence into a gene. The disclosure provides plants, plant parts, plant cells, seeds and grain containing a targeted genetic modificat...

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Bibliographic Details
Main Authors ZHANG, JUN, LAWIT, SHAI, PHILLIPS, JOAN MARIE, FRANK, MARY J, SHEN, BO
Format Patent
LanguageEnglish
Published 18.01.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The disclosure provides plants, plant parts, plant cells, seeds and grain containing a targeted genetic modification that inserts an endogenous microRNA recognition sequence into a gene. The disclosure provides plants, plant parts, plant cells, seeds and grain containing a targeted genetic modification that modifies an endogenous microRNA sequence so that the modified microRNA hybridizes to an endogenous gene. Further provided are methods for decreasing expression of a gene of interest by inserting a microRNA recognition sequence into the gene or modifying an endogenous miRNA sequence to hybridize to the gene
Bibliography:Application Number: US202117813038