ENZYMATIC METHODS FOR CONVERTING LCA AND 3-KCA TO UDCA AND 3-KUDCA

7β-hydroxylation systems are provided, as well as methods for producing ?P-hydroxy derivatives of lithocholic acid and 3-keto-lithocholic acid from such systems. Also provided are recombinant organisms useful for the production of such enzymatic systems, and to plasmids that encode for such enzymes....

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Main Authors REID, J. GREGORY, GREGORY, MATT, REDDY, JAYACHANDRA P, PAUL, BERNHARD J, SCHELL, URSULA
Format Patent
LanguageEnglish
Published 28.12.2023
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Summary:7β-hydroxylation systems are provided, as well as methods for producing ?P-hydroxy derivatives of lithocholic acid and 3-keto-lithocholic acid from such systems. Also provided are recombinant organisms useful for the production of such enzymatic systems, and to plasmids that encode for such enzymes.
Bibliography:Application Number: US202118038203