CRISPR SYSTEMS WITH ENGINEERED DUAL GUIDE NUCLEIC ACIDS
The present invention relates to an engineered Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) system comprising engineered dual guide nucleic acids (e.g., RNAs) capable of activating a CRISPR-Associated (Cas) nuclease, such as a type V-A Cas nuclease. Also provided are methods of...
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Main Authors | , , , |
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Format | Patent |
Language | English |
Published |
21.12.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to an engineered Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) system comprising engineered dual guide nucleic acids (e.g., RNAs) capable of activating a CRISPR-Associated (Cas) nuclease, such as a type V-A Cas nuclease. Also provided are methods of targeting, editing, and/or modifying a nucleic acid using the engineered CRISPR system, and compositions and cells comprising the engineered CRISPR system. |
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Bibliography: | Application Number: US202318190063 |