TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS

Heterobifunctional compounds for targeted protein degradation that include a tricyclic cereblon binder linked to an appropriate protein targeting ligand to degrade a targeted disease-mediating protein of interest are provided.

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Bibliographic Details
Main Authors Henderson, James A, Anderson, Corey Don, Duplessis, Martin, Nasveschuk, Christopher G, Garza, Victoria, Liang, Yanke, Jackson, Katrina L, Moustakim, Moses
Format Patent
LanguageEnglish
Published 23.11.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Heterobifunctional compounds for targeted protein degradation that include a tricyclic cereblon binder linked to an appropriate protein targeting ligand to degrade a targeted disease-mediating protein of interest are provided.
Bibliography:Application Number: US202318134971