BICYCLOHEPTANE PYRROLIDINE OREXIN RECEPTOR AGONISTS

The present invention is directed to bicyclo[4.1 0]heptane pyrrolidine compounds of formula (I) which are agonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders...

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Main Authors Clausen, Dane James, Rudd, Michael T, Wei, Lan, Guiadeen, Deodial Guy, Yang, Dexi, Xiao, Li, Bogen, Stephane L, Hao, Jinsong, Lin, Shishi
Format Patent
LanguageEnglish
Published 16.11.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention is directed to bicyclo[4.1 0]heptane pyrrolidine compounds of formula (I) which are agonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.whereiswherein n is 0 or 1;
Bibliography:Application Number: US202118040896