BICYCLIC [4,6,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS

The present invention relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with HDAC6, having a Formulae I or Formula II:where R, L, X1, X2, X3, X4, X5, Y1, Y2, Y3, and Y4 are described herein.

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Bibliographic Details
Main Authors Lancia, JR., David R, Ng, Pui Yee, Rudnitskaya, Aleksandra, Zheng, Xiaozhang
Format Patent
LanguageEnglish
Published 09.11.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with HDAC6, having a Formulae I or Formula II:where R, L, X1, X2, X3, X4, X5, Y1, Y2, Y3, and Y4 are described herein.
Bibliography:Application Number: US202318196459