Peptides

The present invention relates to novel peptides derived from various target proteins, complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the p...

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Main Authors De Souza, Victoria Arena, Chester, Fiona, Jaykant Sangani, Dhaval, Kleijnen, Maurits, Hood, Graham Anthony, Keating, Garret, Popa, Alina, Mai, Nicole, Brooks, Andrew, Addis, Philip, Gilgunn, Sarah, Powlesland, Alex, Reddy Chillakuri, Chandramouli, Sayer, Christopher, Galfre, Elena, Lim, Alfred, Bombik, Izabela, Pentier, Johanne, Sun, Meidai, Oestringer, Benjamin, Dellacristina, Pietro
Format Patent
LanguageEnglish
Published 02.11.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to novel peptides derived from various target proteins, complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
Bibliography:Application Number: US202218064180