MANUFACTURING PROCESS FOR HIGH TITER ANTIBODY

The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertain...

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Main Authors LaFond, Michelle, Bak, Hanne, Casey, Meghan, Crowley, John, Lawrence, Shawn M, Callinan, Laura, Mellors, Philip, Nicholl, Liam, Oshodi, Shadia Abike, Hourihan, John, Stairs, Robert, Johnson, Amy S, Goh, Hai-Yuan, Corbett, Daniel, Tustian, Andrew, Chiboroski, Mark, Mattila, John, Witmer, Ashley, Conlon, Aishling, Reilly, James, Tang, Xiaolin, Starling, Alessandra, Vartak, Ankit
Format Patent
LanguageEnglish
Published 19.10.2023
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.
Bibliography:Application Number: US202318175852