METHODS TO PRODUCE ROD-DERIVED CONE VIABILITY FACTOR (RDCVF)

The invention is related to methods of producing rod-derived cone viability factor (RdCVF). This invention also relates to the treatment of an ocular disease in a mammal using RdCVF. Also provided are expression vectors for high secreted expression of RdCVF of using nucleotide sequences encoding het...

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Bibliographic Details
Main Authors BRONDYK, William H, O'RIORDAN, Catherine R
Format Patent
LanguageEnglish
Published 12.10.2023
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The invention is related to methods of producing rod-derived cone viability factor (RdCVF). This invention also relates to the treatment of an ocular disease in a mammal using RdCVF. Also provided are expression vectors for high secreted expression of RdCVF of using nucleotide sequences encoding heterologous signal proteins and optionally markers for furin cleavage.
Bibliography:Application Number: US202218066175