Methods and Compositions For Preparing Nucleic Acids For Genetic Analysis

The present disclosure provides methods and compositions for preparing nucleic acid molecules using a novel, single-tube workflow that allows users to carry out the isolation of nucleic acids from a sample and perform a nucleic acid assay using the isolated nucleic acids in a single tube or vessel....

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Bibliographic Details
Main Authors Laliberté, Julie Catherine, Meyers, Jacob, Martin, Patrick Kevin
Format Patent
LanguageEnglish
Published 05.10.2023
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Summary:The present disclosure provides methods and compositions for preparing nucleic acid molecules using a novel, single-tube workflow that allows users to carry out the isolation of nucleic acids from a sample and perform a nucleic acid assay using the isolated nucleic acids in a single tube or vessel. As such, the methods disclosed herein can be used with low quality and/or small quantity of nucleic acid samples. Further, the disclosed methods offer similar or improved concordance rates in addition to improved signal to noise ratio when compared to the existing methods used for genetic analysis. Thus, making the methods disclosed herein suitable for clinical applications such as infectious disease diagnosis, pre-implantation genetic testing, prenatal or cancer diagnosis.
Bibliography:Application Number: US202118022844