COMPOSITIONS AND METHODS FOR IN VIVO GENERATION OF CAR EXPRESSING CELLS

Aspects of this disclosure relate generally to the use of biomaterials for the in vivo generation of CAR expressing cells. In some embodiments, the biomaterials comprise one or more of a cell recruitment composition, a viral vector, and/or a cell activation agent.

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Bibliographic Details
Main Authors Broggi, Maria Anna Sofia, Bridgeman, Chris, Cebe, Regis, Yang, Jennifer, Apsunde, Tushar Dattu, Miller, Sandra, Koshy, Sandeep Tharian, Melles, Yoel, Canham, Stephen Michael, Jayashankar, Shyamali, Price, Andrew Patrick, Granda, Brian Walter, Bardroff, Michael, Guyot, Justine, Lee, Cameron Chuck-munn, Treanor, Louise Mary, Dranoff, Glenn, Rayo, Amy, Skegro, Darko
Format Patent
LanguageEnglish
Published 28.09.2023
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Aspects of this disclosure relate generally to the use of biomaterials for the in vivo generation of CAR expressing cells. In some embodiments, the biomaterials comprise one or more of a cell recruitment composition, a viral vector, and/or a cell activation agent.
Bibliography:Application Number: US202118022058