TDP-43 BIOSENSOR CELL LINES
The present disclosure provides methods for the identification, characterization and ranking of putative tau monomer stabilizing agents. Specifically, the disclosure provides methods for assessing the capability of a test compound to stabilize a tau monomer, methods of prioritizing a plurality of te...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
14.09.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The present disclosure provides methods for the identification, characterization and ranking of putative tau monomer stabilizing agents. Specifically, the disclosure provides methods for assessing the capability of a test compound to stabilize a tau monomer, methods of prioritizing a plurality of test compounds from a library identified as tau monomer stabilizing agents, methods of screening a test compound library to identify tau monomer stabilizing agents, and a kit providing the reagents to perform the described methods. |
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Bibliography: | Application Number: US202118014850 |