ANTIBODIES AGAINST OX-40 AND USES THEREOF

Provided herein are antibodies, or antigen binding portions thereof, that bind to OX40. Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light ch...

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Main Authors CAI, Zhehong, KOZHICH, Alexander T, LEMAR, Hadia, KEMPE, Thomas D, KORMAN, Alan J, QUIGLEY, Michael, CHAKRABORTY, Indrani, MILBURN, Christina Maria, THUDIUM, Kent, SRINIVASAN, Mohan, CHANG, Han, MAURER, Mark, WANG, Xi-Tao, GOKEMEIJER, Jochem, GARCIA, Marie-Michelle Navarro, GUIRNALDA, Patrick, WONG, Susan Chien-Szu, SHAO, Xiang
Format Patent
LanguageEnglish
Published 31.08.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
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Summary:Provided herein are antibodies, or antigen binding portions thereof, that bind to OX40. Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
Bibliography:Application Number: US202217819287