CLASSIFICATION OF NUCLEIC ACID TEMPLATES

Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided...

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Bibliographic Details
Main Authors Travers, Kevin, Turner, Stephen, Korlach, Jonas, Sorenson, Jon, Tomaney, Austin B, Webster, Dale, Marks, Patrick, Heiner, Cheryl, Kislyuk, Andrey, Hanes, Jeremiah, Flusberg, Benjamin
Format Patent
LanguageEnglish
Published 24.08.2023
Subjects
BANDAGES, DRESSINGS OR ABSORBENT PADS
DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS
FILTERS IMPLANTABLE INTO BLOOD VESSELS
FIRST-AID KITS
FOMENTATION
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES
PROSTHESES
TREATMENT OR PROTECTION OF EYES OR EARS
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Summary:Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
Bibliography:Application Number: US202318189075