MACROCYCLIC ETHER CONTAINING INDOLE DERIVATIVES AS INHIBITORS OF MCL-1

The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a subject, pharmaceutical composition comprising such compounds, and their use as MCL-1 inhibitors, useful for treating diseases such as cancer.

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Bibliographic Details
Main Authors REUILLON, Tristan, ROMBOUTS, Frederik Jan Rita, VELTER, Adriana-Ingrid, FERRER CABRERA, Sofia, DE BOECK, Benoît Christian Albert Ghislain, BUIJNSTERS, Petrus Jacobus Johannes Antonius, PESCHIULLI, Aldo
Format Patent
LanguageEnglish
Published 10.08.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a subject, pharmaceutical composition comprising such compounds, and their use as MCL-1 inhibitors, useful for treating diseases such as cancer.
Bibliography:Application Number: US202118004322