Deuterated Pyridopyrimidinones And Their Use As Highly Selective Cyclin-Dependent Kinase 2 Inhibitors

The present invention relates to deuterated pyridopyrimidinone compounds and pharmaceutically acceptable salts thereof with inhibitory activity at cyclin dependent kinase 2 (CDK2) kinase, pharmaceutical composition comprising such compounds and methods of using such compounds for treating diseases a...

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Bibliographic Details
Main Authors Zhang, Shuai, Bian, Wangdong, Wu, Jiaquan, Gao, Minqi, Lu, Zhenghua, Gui, Wenjun, Fan, Feng
Format Patent
LanguageEnglish
Published 03.08.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to deuterated pyridopyrimidinone compounds and pharmaceutically acceptable salts thereof with inhibitory activity at cyclin dependent kinase 2 (CDK2) kinase, pharmaceutical composition comprising such compounds and methods of using such compounds for treating diseases associated with cell-cycle dysregulation.
Bibliography:Application Number: US202118009504