TRICYCLIC COMPOUNDS AS INHIBITORS OF NLRP3

The invention relates to novel compounds for use as inhibitors of NLRP3 inflammasone production, wherein such compounds are as defined by compounds of formula (I) and wherein the integers R1, R2 and R3 are defined in the description, and where the compounds may be useful as medicaments, for instance...

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Bibliographic Details
Main Authors VAN OPDENBOSCH, Nina, DIÉGUEZ-VÁZQUEZ, Alejandro, OEHLRICH, Daniel, LAMKANFI, Mohamed, VAN GOOL, Michiel Luc Maria, CAÑELLAS ROMAN, Santiago
Format Patent
LanguageEnglish
Published 29.06.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention relates to novel compounds for use as inhibitors of NLRP3 inflammasone production, wherein such compounds are as defined by compounds of formula (I) and wherein the integers R1, R2 and R3 are defined in the description, and where the compounds may be useful as medicaments, for instance for use in the treatment of a disease or disorder that is associated with NLRP3 inflammasome activity.
Bibliography:Application Number: US202117996633