METHOD AND SYSTEM FOR IDENTIFYING COLON CANCER-SPECIFIC VESICLE-ASSOCIATED PROTEINS FROM TISSUE SAMPLE

• Main Authors: LASSER, Cecilia, CVJETKOVIC, Aleksander, LOTVALL, Jan
• Format: Patent
• Language: English
• Published: 25.05.2023
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

There is disclosed a method of identifying colon cancer-specific vesicle-associated proteins from a tissue sample of a subject. The method comprises isolating tissue-resident extracellular vesicles from the tissue sample; identifying vesicle-associated proteins associated with the isolated tissue-resident extracellular vesicles; quantifying the identified vesicle-associated proteins to identify one or more major vesicle-associated proteins; creating vesicle-associated protein profiles for the identified vesicle-associated proteins; and comparing the vesicle-associated protein profiles for the identified vesicle-associated proteins with pre-determined vesicle-associated protein profiles of the tumour tissue samples and/or non-tumour tissue samples.