INHIBITION OF SARS-COV-2 VIRAL ENTRY THROUGH ORAL ADMINISTRATION OF LACTOFERRIN AND USES THEREOF

This invention is in the field of medicinal pharmacology. In particular, the present invention relates to pharmaceutical compositions comprising lactoferrin (e.g., naturally occurring lactoferrin, recombinant lactoferrin) which function as inhibitors of severe acute respiratory syndrome coronavirus...

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Bibliographic Details
Main Authors Wotring, Jesse, McCarty, Sean Michael, Mirabelli, Carmen, Sexton, Jonathan Zachary, Weatherwax, Kevin J
Format Patent
LanguageEnglish
Published 18.05.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention is in the field of medicinal pharmacology. In particular, the present invention relates to pharmaceutical compositions comprising lactoferrin (e.g., naturally occurring lactoferrin, recombinant lactoferrin) which function as inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral entry into a subject (e.g., human subject). The invention further relates to methods of preventing, treating and/or ameliorating symptoms related to conditions caused by the SARS-CoV-2 virus (e.g., COVID-19), comprising administering to a subject (e.g., human subject) lactoferrin (e.g., naturally occurring lactoferrin, recombinant lactoferrin) (e.g., oral formulation of lactoferrin, intravenous (IV) formulation of lactoferrin) alone or with additional agents (e.g., remdesivir).
Bibliography:Application Number: US202117920698