DIRECTED CONJUGATION TECHNOLOGIES

Among other things, the present disclosure provides technologies for site-directed conjugation of various moieties of interest to target agents. In some embodiments, the present disclosure utilizes target binding moieties to provide high conjugation efficiency and selectivity. In some embodiments, p...

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Bibliographic Details
Main Authors BERBASOVA, Tetyana, WELSCH, Matthew Ernest, BUNIN, Anna, RASTELLI, Luca, SPIEGEL, David Adam, IBEN, Lawrence Gerald, VIDAL, Christian Marcel, ALVAREZ, Enrique, CUKAN, Michael C, VAILL, Ada Margaret
Format Patent
LanguageEnglish
Published 27.04.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Among other things, the present disclosure provides technologies for site-directed conjugation of various moieties of interest to target agents. In some embodiments, the present disclosure utilizes target binding moieties to provide high conjugation efficiency and selectivity. In some embodiments, provided technologies are useful for preparing antibody conjugates.
Bibliography:Application Number: US202017769924