SYNTHESIS OF GLYCOSYLATED SPHINGOID BASES OF INTEREST OR ANALOGUES THEREOF

The present invention relates to a method for producing a glycosylated sphingoid base of interest or an analogue thereof, the method comprising providing an internalized exogenous precursor and a genetically modified cell, wherein one or more glycosylation reactions can be performed on the exogenous...

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Main Authors Bronikowski, Agathe, Pereira, Fabio, Csaba, Nagy, Soares, Rafael, Mahmoud, Osama, Osztrovszky, Györgyi, Horvath, Ferenc, Dekany, Gyula, Kovacs-Penzes, Piroska, Silva Neves, Dário Jorge, Santos, Jorge
Format Patent
LanguageEnglish
Published 30.03.2023
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Summary:The present invention relates to a method for producing a glycosylated sphingoid base of interest or an analogue thereof, the method comprising providing an internalized exogenous precursor and a genetically modified cell, wherein one or more glycosylation reactions can be performed on the exogenous precursor in the genetically modified cell, the genetically modified cell comprising one or more nucleic acid sequences encoding one or more glycosyltransferase enzymes.
Bibliography:Application Number: US202117801642