OMECAMTIV MECARBIL TABLET

Provided herein are tablet formulations comprising a core comprising omecamtiv mecarbil, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable hydrate of a pharmaceutically acceptable salt thereof; a filler; a binder; a glidant; and a lubricant; and a film coating on the core,...

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Bibliographic Details
Main Authors KIANG, Yuan-Hon, BI, Mingda, LOU, Hao
Format Patent
LanguageEnglish
Published 23.03.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Provided herein are tablet formulations comprising a core comprising omecamtiv mecarbil, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable hydrate of a pharmaceutically acceptable salt thereof; a filler; a binder; a glidant; and a lubricant; and a film coating on the core, the film coating comprising a modified-release polymer and a pore former. Also provided is a process for making a tablet formulation and a method of treating cardiovascular conditions, such as heart failure, using the tablet formulation.
Bibliography:Application Number: US202117798531