JAK INHIBITORS CONTAINING A 4-MEMBERED HETEROCYCLIC AMIDE

The invention provides compounds of formula (I):which contain a 4-membered heterocyclic amide, where the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions compri...

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Bibliographic Details
Main Authors FATHEREE, PAUL R, SMITH, CAMERON, CRATER, GLENN D, KLEINSCHEK, MELANIE A, BRANDT, GARY E.L, SULLIVAN, STEVEN D.E, VAN ORDEN, LORI JEAN
Format Patent
LanguageEnglish
Published 02.03.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides compounds of formula (I):which contain a 4-membered heterocyclic amide, where the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat respiratory diseases, and processes and intermediates useful for preparing such compounds.
Bibliography:Application Number: US202217885475