TETRAHYDROBENZO-QUINOLINE SULFONAMIDE DERIVATIVES USEFUL AS IGE MODULATORS

The present invention relates to tetrahydrobenzo-isoquinoline sulfonamide derivatives of formula (1), processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain a...

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Bibliographic Details
Main Authors NORMAN, Timothy John, YOUSUF, Zeshan, HEER, Jag Paul, SUGANTHAN, Selvaratnam
Format Patent
LanguageEnglish
Published 16.02.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates to tetrahydrobenzo-isoquinoline sulfonamide derivatives of formula (1), processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain autoimmune responses), and in particular disorders caused by the interaction of IgE with the FcεRI receptor.
Bibliography:Application Number: US202017786309